Global Single-use Bioreactor Market by Product; by Type; by Cell Type; by Molecule Type; by Applications; by Region (North America, Europe, Asia-pacific, Latin America, Middle East Africa): Global Forecasts 2021 To 2027

The Global Single-use Bioreactor Market was valued at USD 3.3 Bn in 2020 and is expected to reach USD 12.4 Bn by 2027, with a growing CAGR of 21% during the forecast period.

Single-use Bioreactor Market Definition

Single-use bioreactor is also known as disposable bioreactor which is designed with a disposable bag instead of culture vessel. In this type of bioreactor, the lining of bioreactor that will be in contact with the cell culture will be plastic and this lining hold permanent structure (cuboid, cylinder or a rocker steel support). Single-use bioreactor is widely used in pharmaceutical and biotechnological companies for buffer, cell harvesting, growth media preparation, purification, and virus inactivation.

Single-use Bioreactor Market

Single-use Bioreactor Market Dynamics

The driving factors for the global single-use bioreactor market include rising demand of single-use bioreactor for culture preparation which avoid the contamination & mixing of one media with other and increasing use of culture media for vaccine development. Single-use bioreactor offer set of benefits which include cost-effectiveness, negligible contamination, and these bioreactors have less maintenance cost on mechanical end. These factors contribute to the rising demand of single-use bioreactor in the ecosystem during the forecast period. Besides, availability of wide range of single-use bioreactors in terms of volume, size, dimension, and temperature control rises the demand of single-use bioreactor and help to leverage the growth of single-use bioreactor demand across the globe during the forecast period. Increase in research activities and growing collaborations of research & academic labs with companies leverage the growth of single-use bioreactor demand during the forecast period. For instance, in 2018, Novartis (Switzerland) teamed up with Wyss Institute for Biologically Inspired Engineering (US) at Harvard University and the Dana-Farber Cancer Institute (US) for research and development of implantable and injectable systems that can strengthen patient's immune response to different types of cancer. For the development of injectables, single-use bioreactors were used to carry out the reactions for single use purpose on lab-scale molecule development. Such growing demand of single-use bioreactor for research is expected to uplift the growth of single-use bioreactor demand during the forecast period.

Global Single-use Bioreactor Market Segmentation:

By Product

  • Single-use Bioreactor System
  • Single-use Filtration Assemblies
  • Single-use Media Bags
  • Others

By Type

  • Wave-Induced
  • Stirred- Tank
  • Bubble-Column

By Cell Type

  • Bacterial Cells
  • Mammalian Cells
  • Yeast Cells
  • Others

By Molecule Type

  • Vaccines
  • Monoclonal Antibodies
  • Stem Cells
  • Gene-Modified Cells
  • Others

By Applications

  • Process Development
  • Research and Development
  • Bioproduction

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East & Africa

Company Profiles and Competitive Intelligence

The key players operating in the single-use bioreactor market are:

  • Sartorius Stedim Biotech
  • Thermo Fisher Scientific
  • Danaher Corporation
  • Merck KGaA
  • Getinge AB
  • Eppendorf AG
  • CESCO Bioengineering
  • Cellexus
  • PBS Biotech Inc.
  • Distek Inc.
  • ABEC Able Corporation & Biott Corporation
  • G&G Technologies Inc.
  • Solida Biotech GmBH
  • Satake Chemical Equipment Mfg., Ltd
  • Stobbe Pharma GmBH
  • Celltainer Biotech BV
  •  Meissner Filtration Products Inc.
  •  bbi-biotech GmBH
  •  ENDEL ENGIE
  •  OmniBRx biotechnologies
  •  New Horizon Biotechnology Inc.
  •  GPC Bio
  •  Cell culture company
  •  Aptus bioreactors
  • Others

Based on type, stirred-tank segment is expected to contribute highest to the growth of the market during forecast period due to rise in its use in aerobic microbial culture

Based on type, single-use bioreactor market is broadly segmented into wave-induced, stirred- tank, and bubble-column. Stirred-tank held the largest market share in 2020 due to increased aerobic-culture based research activities and is expected to increase more during the forecast period owing to rising application of oxygen to carry out microbial reactions. Moreover, growing research activities and increasing use of stirred-tank single-use bioreactor for large-scale production in companies boost the growth of the segment in the single-use bioreactor demand during the forecast period. Besides, parameters such as better mixing, and oxygen transfer is expected to trigger the demand of stirred-tank bioreactors and helps to uplift the growth of single-use bioreactor during the forecast period.

Based on cell type, mammalian segment is expected to dominate the market during forecast period due to rise in research in biologics and human cells

Based on cell type, single-use bioreactor market is broadly segmented into bacterial cells, mammalian cells, and yeast cells. Mammalian segment is expected to hold the largest market share during forecast period due to increase in research on cancer cells, viral vaccines, and therapeutic proteins. Moreover, increasing use of mammalian cell using single-use bioreactor in biopharmaceutical companies based on methotrexate amplification technology or glutamine synthetase system is expected to boost the growth of segment in single-use bioreactor demand during forecast period. In addition, rising cultivation of animal cells for research purpose is further expected to stimulate the single-use bioreactor demand in the industry during the forecast period. Mammalian cell culture is extensively used in manufacturing industries which witnesses in increasing adoption of disposable or single-use bioreactor devices during the forecast period.

Based on region, North America is expected to increase more during the forecast period due to rising presence of biopharmaceutical industries in this region

Based on region, North America is expected to dominate the market during forecast period due to presence of research infrastructure and availability of strong government support in terms of funding. Moreover, rising number of key operating players in North America and increasing prevalence of chronic infectious diseases such as HIV, hepatitis and mosquito transmitted diseases are expected to leverage the growth of single-use bioreactor demand in the market during forecast period.

The report also provides an in-depth analysis of Single-use Bioreactor market dynamics such as drivers, restraints, opportunities, and challenges

Drivers

  • Increase in biopharmaceutical production
  • Growing biologics which uses cellular as a component for formulation development
  • Rising demand for single use reaction container due to flexibility

Restraints

  • Availability of large range of alternative bioreactor products
  • Lack of skilled professionals
  • High-cost product

Opportunity

  • Expansion of single use bioreactor market in emerging countries such as India, China, and Mexico

Challenges

  • Single use bioreactor limits the liquid transfer
  • Issues related to scalability

COVID-19 Impact on the Single-use Bioreactor Market Analysis

Covid-19 has positively impacted the growth of single-use bioreactor market due to rising demand for use of disposable bioreactors for vaccine development. Moreover, during pandemic, rising concern for contamination of vessel or flask by multiple use and generating need for sterile bioreactor for viral reactions are expected to leverage the growth of single-use bioreactor market during forecast period. Many biotechnological and pharmaceutical companies adopted the use of single-use bioreactors for vaccine development or clinical test phase has increased the single-use bioreactor demand and this is expected to boost the growth of single-use bioreactor during forecast period. For instance, in March 2020, Sartorious (Germany) helped CanSino Biologics Inc. (China), and Maj.Gen Che Wei’s team for the research and development of the first vaccine candidate against covid-19 to enter in clinical trials at Institute of Bioengineering at the Academy of Military Medical Sciences in China. Such collaboration for development of therapy against novel coronavirus is expected to boost the growth of single-use bioreactor during forecast period. On the contrary, there is decline in spending on global pharmaceutical R&D and fall off in biologics sale in 2020 due to sudden covid-19 outbreak is have significant impact on growth of single-use bioreactor market during the forecast period.

The report also provides an in-depth analysis of key trends in single-use bioreactor market

Sr. No. Trends Impact
1 Rising application of single use bioreactor in multiple drug facilities Positive
2 Growing advances in designing, controlling, data logging, and automation level of single use bioreactors Positive

The report also provides an in-depth analysis of recent news developments and investments

  • In March 2021, Thermo Fisher Scientific (US) launched single-use bioreactors on large scale with capacities of 3000 and 5000 L for bioprocess industry for clinical and commercial use. These bioreactors were launched by looking at the strong demand for large scale single-use bioreactors for therapeutic development. This launch is expected to elevate the revenue of the company due to rising demand and is expected to expand the single-use bioreactor portfolio & offering of the company.
  • In August 2021, PBS Biotech (US) expanded single-use bioreactor technology to fulfil growing cell therapy demand across the world. PBS mentioned the suitability of their single-use bioreactor for advanced therapy in allogeneic cell therapies. This offering is expected to provide a technological support for bioreactors in research and development and this is expected to broaden their single-use bioreactor portfolio in the market.

The unique insights provided by this report also includes the following:

  • In-depth Value Chain Analysis
  • Opportunity Mapping
  • Sector Snapshot
  • Key Players Positioning Matrix
  • Regulatory Scenario
  • Strategies Adopted-Benchmarking Heat Map
  • Market Trends
  • Covid-19 Impact Analysis
  • Product Comparison
  • Pre & Post COVID 19 Impacts on Single-use Bioreactor Market
  • Competitive Landscape

 

Frequently Asked Questions (FAQs)

The global market was valued at USD 3.3 Bn in 2020 and is anticipated to reach USD 12.4 Bn by 2027.

The global market is estimated to grow at a compound annual growth rate (CAGR) of 21% during forecast period.

In the base year 2020, North America accounted for largest share in the market

Lack of trained professionals and inflated cost of device for repetitive use restraint the growth of market.

As per expert opinions, increasing incidences of chronic diseases, growing demand for disposable bioreactor containers, and government spending on healthcare will drive the growth of market.

Few key players include, but not limit up to: Sartorius Stedim Biotech, Thermo Fisher Scientific, Danaher Corporation, Merck KGaA, Getinge AB, Eppendorf AG, CESCO Bioengineering, Cellexus, PBS Biotech Inc., Distek Inc., and ABEC Able Corporation & Biott Corporation.

Related Reports

Need specific market information ?

Ask for free product review call with the author

Share your specific research requirements for a customized report

Request for due diligence and consumer centric studies

Request for study updates, segment specific and country level reports

  1.  Introduction
    1. Product Outline
    2. What is Single-use Bioreactor?
    3. Analysis of Single-use Bioreactor Market
    4. Covid -19 Impact
    5. Market Dynamics
      1. Drivers
      2. Restraints
      3. Opportunities
      4. Threats
    6. Technology Overview
  2. Regulatory Landscape for Single-use Bioreactor Market
    1. Regulations and Standards
  3. Single-use Bioreactor Market by Product
    1. Single-use Bioreactor System
    2.  Single-use Filtration Assemblies
    3.  Single-use Media Bags
    4. Others
  4. Single-use Bioreactor Market, by Type
    1. Wave-Induced
    2.  Stirred- Tank
    3. Bubble-Column
  5. Single-use Bioreactor Market, by Cell Type
    1. Bacterial Cells
    2. Mammalian Cells
    3. Yeast Cells
    4. Others
  6. Single-use Bioreactor Market, by Molecule Type
    1. Vaccines
    2. Monoclonal Antibodies
    3.  Stem Cells
    4.  Gene-Modified Cells
    5.  Others
  7. Single-use Bioreactor Market, by Application
    1. Process Development
    2.  Research and Development
    3.  Bioproduction
  8. Regional Analysis
    1. North America
      1. US
      2. Canada
    2. Europe
      1. Germany
      2. UK
      3. France 
      4. Spain
      5. Italy
      6. Rest Of Europe
    3. Asia Pacific
      1. China
      2. India
      3. Japan
      4. Australia
      5. Rest Of Asia Pacific
    4. Latin America
      1. Brazil
      2. Mexico
      3. Rest of Latin America
    5. Middle East Africa (MEA)
      1. GCC
      2. Rest of MEA
  9. Key Strategic Insights
    1. New Applications
    2. Emerging Technologies
    3. Opportunity Mapping
    4. Critical Success Factors
    5. Customer Preferences
  10. Key Market Trends / Recent Developments
  11. Competitive Scenario
    1. Mergers and Acquisitions
    2. Investments
    3. Joint Ventures
    4. New Product launches
    5. Presence of Players by Geographies
  12. Key global players
    1. Sartorius Stedim Biotech
    2. Thermo Fisher Scientific
    3. Danaher Corporation
    4. Merck KGaA
    5. Getinge AB
    6. Eppendorf AG
    7. CESCO Bioengineering
    8. Cellexus
    9. PBS Biotech Inc.
    10. Distek Inc.
    11. ABEC Able Corporation & Biott Corporation
    12. G&G Technologies Inc.
    13. Solida Biotech GmBH
    14. Satake Chemical Equipment Mfg., Ltd
    15. Stobbe Pharma GmBH
    16. Others

Choose License

License Type
Ask for Customization

Why Choose AllTheResearch?

  • Monthly market updates for 6 months
  • Online access of reports
  • Options to buy sections of report
  • Critically analysed research on Quadrant Positioning of your company.
  • Syndicated report along with a supplementary report with objective-based study
  • Get profiled in the reports.Expanding your visibility across our network of readers and viewers
  • We provide local market data in local language on request
  • A complementary co-branded white paper
  • Flat consulting fee based exclusive studies. Consult at the price of syndicate
  • Access to expert team for free transaction advisory service.
Speak to Analyst

Quick Inquiry

Follow Us

Choose License

License Type
Ask for Customization