PD-1 and PD-L1 Inhibitors Market is Expected to Grow at a CAGR of 19.8% by 2027


The increasing prevalence of the lung cancer among the population fuels the global PD-1 and PD-L1 inhibitors market growthThe Global PD-1 and PD-L1 Inhibitors Market was valued at USD 33.1 billion in 2020, and it is expected to reach USD 117.2 billion by 2027, with a CAGR of 19.8% during the forecast period.

The major driving factors of the PD-1 and PD-L1 inhibitors market growth includes rising prevalence of non-small cell lung cancer due to change in lifestyle in the developed and developing regions. The adoption of  PD-1 and PD-L1 inhibitors proves as a more efficient treatment for the solid tumours and blood related tumour cancer which is considerably driving factors influencing the growth of the global PD-1 and PD-L1 market. For example, according to statics given by ThermoFisher Scientific among all types of the cancer solid tumours holds over 40% of share. 

The PD-1 and PD-L1 inhibitors are used as first line treatment for the cancer. It is used before chemotherapy to treat the cancer. However, these are the boosting factors for the growth of global PD-1 and PD-L1 inhibitors market. Increasing investment in R&D sector of PD-1 and PD-L1 inhibitors drug development creates tremendous opportunity for the growth of PD-1 and PD-L1 inhibitors market. Further, the increasing number of PD-1 and PD-L1 inhibitors drugs in the pipeline is considerably the major opportunity to positively drive the global PD-1 and PD-L1 inhibitors market.

However, the high cost of PD-1 and PD-L1 inhibitors drugs is the restraining factor for the growth of the PD-1 and PD-L1 inhibitors market. Additionally, the safety concern and side effects of the drug hinders the growth of global PD-1 and PD-L1 inhibitors market.

Global PD-1 and PD-L1 Inhibitors Market by Application Outlook (Revenue, USD Billion, 2021-2027)

  • Solid Tumours
  • Tumours Related to Blood

In the application segment, the solid tumours segment is the fastest growing sub segment and are followed by the tumours related to blood for PD-1 and PD-L1 inhibitors market. Solid tumour includes the sarcomas, lymphomas, and carcinomas whereas tumours related to blood includes myeloma, lymphoma, and leukemia. The increasing patient pool of various cancer such as lung cancer, bone cancer, breast cancer, colon cancer and others including solid tumors is considerably driving the growth of solid tumors sub-segment.

The Global PD-1 and PD-L1 Inhibitors Market Segmentation:

Global PD-1 and PD-L1 Inhibitors Market by Type Outlook (Revenue, USD Billion, 2021-2027)

  • PD-1 Inhibitor
  • PD-L1 Inhibitor

Global PD-1 and PD-L1 Inhibitors Market by Region Outlook (Revenue, USD Billion, 2021-2027)

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

Key Findings:

  • Based on the type, the PD-1 segment held the largest market share in 2020
  • Based on application, solid tumours segment shows the highest growth rate over the forecast period and followed by tumours related to blood sub-segment

Company Profiles and Competitive Intelligence

The key players operating in the global PD-1 and PD-L1 inhibitors market are:

  • Gilead Sciences
  • Merck & Co.
  • Bristol-Myers Squibb
  • AstraZeneca
  • Sanofi
  • F. Hoffmann-La Roche AG
  • Celgene
  • Pfizer
  • Amgen
  • Novartis
  • BeiGene
  • Hengrui Pharmaceutical
  • Jiangsu Hengrui Medicine Company Ltd.
  • Regeneron Pharmaceuticals Inc.
  • Ono Pharmaceutical Co., Ltd.
  • Innovent Biologics
  • Shanghai Junshi Biosciences
  • GLAXOSMITHKLINE
  • Lilly
  • Lupin Biotech Ltd.

Recent News:

  • In December 2018, Hengrui’s inhibitor PD-1 drug is affected due to slow speed of drug approval than expected.  
  • In June 2021, European Commission approved the Bristol Myers Squibb company’s ipilimumab (Plus Yervoy), and nivolumab (Opdivo) drugs to treat the deficiency of mismatch repair in server metastatic colorectal cancer.

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